CTNNB1 Connect & Cure is proud to announce a research grant award to Dr. Damon Page at Seattle Children’s and the University of Washington, funded in partnership with CURE Epilepsy. This project was selected as the recipient of the 2025 Rare Epilepsy Partnership Award and will be supported through a $50,000 matching grant. This study represents…
Thanks to the support of our community, CTNNB1 Connect and Cure has awarded an additional $50,000 to Dr. Michele Jacob’s lab at Tufts University to support six more months of research advancing a potential therapy for CTNNB1 syndrome. This funding supports our drug discovery collaboration led by Dr. Michele Jacob at Tufts University, together with scientists…
Dear CTNNB1 Community, We are beyond thrilled to share exciting news from a groundbreaking research project fully funded by CTNNB1 Connect and Cure — made possible by your fundraising efforts and generosity! Thanks to this incredible community, we were able to support a study led by Dr. Clement Chow at the University of Utah, where his…
A recent study published in Molecular Therapy – Nucleic Acids introduces a promising therapeutic approach for CTNNB1 Syndrome, a rare genetic disorder characterized by severe intellectual disabilities, motor delays, and other neurological impairments. The research focuses on a novel gene therapy technique that aims to restore normal function of the CTNNB1 gene. In this study, researchers utilized advanced…
The Chan Zuckerberg Initiative and Citizen Health have announced a strategic investment and partnership to drive drug development and accelerate cures for rare diseases. Ctnnb1 Connect & Cure is proud to be part of this rare disease movement, with many of our members already using Citizen Health to share their de-identified data and contribute to critical…
Researchers at Tufts University School of Medicine and the Graduate School of Biomedical Sciences (GSBS) have identified a small molecule that, in mouse and human cell models, rectifies the underlying molecular cause of a rare genetic developmental disorder linked with motor and intellectual disabilities and some types of autism spectrum disorder. Their most recent research, published in EMBO Molecular Medicine, provides the…