Induced Pluripotent Stem Cells (iPSCs)
CTNNB1 DNA Variant | CTNNB1 Protein Variant | Source | Notes |
---|---|---|---|
211dupT | Ser71Phefs*11 | SFARI | Request here |
514_518dupGCAGT | Met174Glnfs*37 | SFARI | Request here |
1962T>A | Tyr654* | SFARI | Request here |
1469_1488del | Gly490Alafs*33 | SFARI | Request here |
283C>T | Arg95* | SFARI | Request here |
981_982delAA | Met328Glufs*24 | SFARI | Request here |
1354_1357delCTTC | Leu452Glyfs*19 | SFARI | Request here |
Animal Models
Ctnnb1⁺⁄⁻
Species: Mouse
Background Strain: Hybrid mix of background strains C57B6/J; 129/SvJ; FVB CTNNB1
Genetic Modifications: Deletion of exons 2-6 resulting in loss of functional β-catenin protein
Source: M. Jacob, Tufts University, Boston, MA
References: PMID 39103699
To request, please email michele.jacob@tufts.edu
C3.Cg-Ctnnb1ᴮᶠᶜ/H
Species: Mouse
Background Strain: (C3H/HeNCrl x BALB/cAnNCrl)F1
Genetic Modifications: ENU mutagenesis induced a C to A transversion that results in the amino acid substitution of lysine for threonine at position 653 (T653K)
Source: UKRI-MRC Harwell Institute, United Kingdom
References: PMID 24614104
To request, please visit https://archive.har.mrc.ac.uk/stock?id=000065